Replacing solubilizer with lipid microspheres eliminates the severe adverse reaction of vitamin K1 injection

Yan-Ni MI

Replacing solubilizer with lipid microspheres eliminates the severe adverse reaction of vitamin K1 injection / 中国药学杂志

Yan-Ni MI.

Chinese Pharmaceutical Journal ; (24): 1832-1835, 2014.

Article in Chinese | WPRIM | ID: wpr-860042

ABSTRACT

ABSTRACT

OBJECTIVE:

To investigate whether substituting the solubilizer with lipid microspheres in vitamin K1 injection can eliminate the anaphylactoid reaction.

Anaphylactoid reaction; Anaphylaxis; Beagle dog; Injection; Lipid microsphere; RBL-2H3 cell; Vitamin K1

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Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Pharmaceutical Journal Year: 2014 Type: Article