Progress in dipeptidyl peptidase-4 and its inhibitors / 中国药学杂志
Chinese Pharmaceutical Journal
;
(24): 1789-1796, 2014.
Article
in Chinese
| WPRIM
| ID: wpr-860145
ABSTRACT
OBJECTIVE:
To review the structures of dipeptidyl peptidase-4 (DPP-4) and its inhibitors and introduce the evaluation methods of several marketed inhibitors.METHODS:
Preparation of this review is based on searching, categorizing, analyzing and summarizing of diplomatic and international literatures about DPP-4 and its inhibitors. RESULTS ANDCONCLUSION:
DPP-4 has attracted a lot of attention as a new target of type 2 diabetes, and some drug candidates have been developed and entered clinical phases. The structure-activity relationship study of various reported inhibitors could promote the development of more efficient DPP-4 inhibitors.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Pharmaceutical Journal
Year:
2014
Type:
Article
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