Molecular structure and pharmacological characteristics of DPP4 inhibitors / 中国药学杂志

ABSTRACT

OBJECTIVE: To review the molecular structure and pharmacological characteristics of DPP-4 inhibitors. METHODS: based on the research literatures in recent years, reviewed the history and development of incretin in diabetes management, especially the R & D process and the molecular structure, pharmacodynamic / pharmacokinetic (PK/PD) and clinical efficacy of DPP-4 inhibitors. RESULTS and CONCLUSION: DPP-4 inhibitors have many advantages and good future in diabetes care.