Chemical constituents of Dendrobium devonianum / 中国药学杂志

ABSTRACT

OBJECTIVE: To study the chemical constituents of Dendrobium devonianum. METHODS: The compounds were isolated and purified by means of column chromatography with silica gel, Sephadex LH-20 and prep- HPLC. Their structures were identified on the basis of physicochemical parameters and spectroscopic data comparison with standard literature data. RESULTS: Twenty-five compounds were isolated from the 95% ethanol extract of D. devonianum, and identified as 3-hydroxy-4', 5-dimethoxybibenzyl(1), tristin(2), 3, 4', 5-trihydroxybibenzyl(3), N-trans-coumaroyltyramine(4), N-trans- caffeoyltyramine(5), p-hydroxyphenylpropionyltyramine(6), N-cis-coumaroyltyramine(7), 2, 5-dihydroxy-4-methoxy-9, 10-dihydrophenanthrene(8), 2, 4, 7-trihydroxy-9, 10-dihydrophenanthrene(9), 4', 5, 7-trihydroxy-flavonol(10), dihydroconifery acetate(11), ethyl 4-hydroxycinnamate(12), p-hydroxycinnamic acid(13), p-hydroxyphenylpropionic acid(14), 4-hydroxybenzoic acid(15), protocatechuic acid(16), erigeside II(17), citrusin C(18), dihydrosyringin(19), leonuriside A(20), adenosine(21), β-sitosterol(22), daucosterol(23), (+)-syringgaresinol-O-β-D-glucopyranoside(24) and sucrose(25). CONCLUSION: Compounds 1-21 and 24-25 are obtained from this plant for the first time. Compound 1 is isolated from the Dendrobium genus for the first time. Compounds 5, 7, 11, 12 and 18 are obtained from Orchidaceae for the first time.