Quality analysis of Mingmu Shangqing tablets / 中国药学杂志

ABSTRACT

OBJECTIVE: To investigate the status of the quality of Mingmu Shangqing tablets and to carry out exploratory research on its quality standard. METHODS: Thirty-four batches of samples were tested according to the current quality standard in Pharmacopoeia of the People's Republic of China (2010) Volume I. The exploratory research including microscopic identification of the raw powders, analysis of the volatile constituents by GC, determination of the characteristic components of prepared Radix Et Rhizoma Rhei and Radix Glycytthiae by HPLC, and determination of the active components of Fructus Gardeniae, Radix Paeoniae Rubra, Fructus Aurantii, Pericarpium citri Reticulatae, and Radix Scutellariae by HPLC-DAD. RESULTS: Thirty-three batches (97.1%) met the current quality standard. CONCLUSION: The exploratory research can increase the specificity, controllability and safety of the quality standard of Mingmu Shangqing tablets. It will provide reference for further revise of the drug standard and monitoring the drug quality.