Simultaneous determination of flavones in Shuanghuanglian preparations by both QAMS and external standard method / 中国药学杂志
Chinese Pharmaceutical Journal
;
(24): 1665-1669, 2012.
Article
in Chinese
| WPRIM
| ID: wpr-860599
ABSTRACT
OBJECTIVE:
To study the feasibility of quantitative analysis of multi-components by single-marker (QAMS) in determination of flavones in Shuanghuanglian preparations by comparing the results assayed by QAMS and external standard method (ESM).METHODS:
The analysis was performed on a Xtimate™ C18 column (4.6 mm × 250 mm, 5 μm)with methanol and water containing 0.2% phosphoric acid as the mobile phase in gradient elution. The flow rate was set at 1.0 mL · min-1. The UV detector wavelength was 274 nm, and the column temperature was 30°C.RESULTS:
Within the linear ranges, the analysis results showed no significant difference between QAMS and ESM.CONCLUSION:
The QAMS method is credible and will be a new quality evaluation pattern for the determination of multiple flavones in Shuanghuanglian preparations.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Pharmaceutical Journal
Year:
2012
Type:
Article
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