GSnet: An Integrated Tool for Gene Set Analysis and Visualization
Genomics & Informatics
;
: 133-136, 2007.
Article
in English
| WPRIM
| ID: wpr-86061
ABSTRACT
The Gene Set network viewer (GSnet) visualizes the functional enrichment of a given gene set with a protein interaction network and is implemented as a plug-in for the Cytoscape platform. The functional enrichment of a given gene set is calculated using a hypergeometric test based on the Gene Ontology annotation. The protein interaction network is estimated using public data. Set operations allow a complex protein interaction network to be decomposed into a functionally-enriched module of interest. GSnet provides a new framework for gene set analysis by integrating a priori knowledge of a biological network with functional enrichment analysis.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Microarray Analysis
/
Protein Interaction Maps
/
Gene Ontology
Language:
English
Journal:
Genomics & Informatics
Year:
2007
Type:
Article
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