Study on preparation and standardization of reference standard of chondroitin substance sodium / 中国药学杂志
Chinese Pharmaceutical Journal
;
(24): 236-238, 2012.
Article
in Chinese
| WPRIM
| ID: wpr-860838
ABSTRACT
OBJECTIVE:
to establish a national reference substance for chondroitin sulfate sodium.METHODS:
Identification of chondroitin sulfate sodium was carried out by infrared(IR) and high performance liquid chromatography(HPLC). A high performance size exclusion chromatography in conjunction with refractive index detector and multi-angle laser light scatter(MALLS) was used to determine the molecular weight and molecular weight distribution of chondroitin sulfate sodium. The content of chondroitin sulfate sodium was calculated by mass balance method.RESULTS:
The content of chondroitin sulfate sodium reference substance was 99.1%.CONCLUSION:
The establishment of national reference substance of chondroitin sulfate sodium can effectively control the quality of the product. Copyright 2012 by the Chinese Pharmaceutical Association.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Pharmaceutical Journal
Year:
2012
Type:
Article
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