Impact factors of the outcome of venous-arterial extracorporeal membrane oxygenation weaning in patients with cardiogenic shock / 中国医学影像技术

ABSTRACT

Objective:To explore the impact factors of the outcome of venous-arterial extracorporeal membrane oxygenation (V-A ECMO) in patients with cardiogenic shock. Methods: Totally 37 cardiogenic shock patients who received V-A ECMO support were retrospectively analyzed. The patients were divided into tolerance group and intolerance group according to results of tolerance tests, and those in tolerance group were then divided into successful weaning subgroup (weaning and survival within 30 days) and failed weaning subgroup. The baseline data of patients in tolerance group and intolerance group were compared. The hemodynamic parameters measured with echocardiography were compared between successful weaning subgroup and failed weaning subgroup at the lowest flow during the weaning trial. Results: There were 32 patients in tolerance group and 5 in intolerance group. Among tolerance group, there were 22 cases in successful weaning subgroup and 7 in failed weaning subgroup,while 3 patients died within 30 days. Age (P=0.04) and bleeding rate (P0.05). During the weaning trial, venous oxygen saturation (SvO2), left ventricular outflow tract velocity-time integral (LVOT-VTI), left ventricular ejection fraction (LVEF) and mitral annulus lateral wall systolic velocity (Sa) of successful weaning subgroup were all higher than those of failed weaning subgroup (all P<0.05). Conclusion: SvO2, LVOT-VTI, LVEF and Sa were the impcat factors of outcome of V-A ECMO in patients with cardiogenic shock.