Comparison on radiation dose of contrast-enhanced mammography and full-field digital mammography / 中国医学影像技术

ABSTRACT

Objective To compare breast radiation dose between contrast-enhanced mammography (CEM) and full-field digital mammography (FFDM), and to explore the correlation of breast radiation dose with gland compression thickness. Methods The average gland dose (AGD) of FFDM and CEM were compared through phantom experiment on the same mammography device. Totally 102 patients with breast disease underwent CEM (CEM group), while other 104 underwent FFDM (FFDM group) on the same machine, and AGD and gland compression thickness were recorded. Based on the 5th breast imaging-reporting and data system (BI-RADS) of American college of radiology (ACR), the breasts were divided into dense glands and non-dense glands. The differences of AGD and gland compression thickness were compared between 2 groups and among different types of glands, and the correlations of AGD and gland compression thickness were analyzed. Results AGD of low-energy CEM and FFDM were similar in phantom experiment. There were 22 non-dense glands and 80 dense glands in CEM group, 39 non-dense glands and 65 dense glands in FFDM group. No significant difference in gland compression thickness was found between 2 groups (U=4 823.50, P>0.05). There was no statistical difference of the AGD in CEM group and AGD of FFDM group (U=5 249.50, P>0.05), while AGD of low energy CEM was lower than that of FFDM group (U=2 111.00, P0.05). The AGD of dense glands was higher than that of non-dense glands in FFDM group (U=846.50, P0.05). Conclusion The overall ADC of CEM was comparable to that of FFDM. The thinner the gland compression thickness is, the lower the radiation dose is. CEM had more advantageous for dense breasts than for non-dense glands.