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Clinical features and imaging findings of adrenocortical carcinoma in children / 中国医学影像技术
Chinese Journal of Medical Imaging Technology ; (12): 1495-1498, 2020.
Article in Chinese | WPRIM | ID: wpr-860879
ABSTRACT

Objective:

To observe clinical features and imaging findings of children adrenocortical carcinoma (ACC).

Methods:

Clinical and imaging data of 13 children with ACC confirmed by pathology were retrospectively analyzed. Among them, 11 cases received preoperative abdominal CT and 4 cases received preoperative abdominal MR scanning. The clinical and imaging manifestations of ACC were observed.

Results:

Among 13 ACC children, 10 (10/13, 76.92%) were female, and most common clinical manifestations included obvious masculinization (9/13, 69.23%), Cushing syndrome (4/13, 30.77%), clitoral hypertrophy (3/13, 23.08%), pubic hair presbyopia (3/13, 23.08%), abdominal pain and abdominal mass (2/13, 15.38%). Ten children (10/13, 76.92%) had elevated serum androgen. CT showed largeadrenal masses with maximum diameter>6 cm in 7 cases (7/13, 53.85%), the lesions were lobulated in 8 (8/13, 61.54%) cases. Among 13 lesions, 5 (5/11, 45.45%) had uneven density with calcification foci. All lesions unevenly and obviously enhanced after enhancement (11/11, 100%), and "network-like" changes were observed in 8 cases (8/11, 72.23%). Tumor involvement of surrounding tissue and renal vein or inferior vena cava tumor thrombi were noticed in 2 cases (2/11, 18.18%). MR T2WI showed slightly high signal lesions in 3 cases and medium signal lesion in 1 case, all uneven enhanced after enhancement.

Conclusion:

Imaging manifestations of children ACC had certain characteristics, combining with clinical manifestations were helpful to diagnosis of this disease.

Full text: Available Index: WPRIM (Western Pacific) Type of study: Diagnostic study Language: Chinese Journal: Chinese Journal of Medical Imaging Technology Year: 2020 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Type of study: Diagnostic study Language: Chinese Journal: Chinese Journal of Medical Imaging Technology Year: 2020 Type: Article