The clinical study of 37 pregnancy women with aplastic anemia / 대한산부인과학회잡지
Korean Journal of Obstetrics and Gynecology
;
: 2536-2541, 1999.
Article
in Korean
| WPRIM
| ID: wpr-8609
ABSTRACT
Objectives:
To determine whether the clinical aspect of aplastic anemia is influenced by pregnancy.METHODS:
We reviewed 37 cases of pregnant aplastic anemia patients during Jan. 1989 to Dec. 1998, and examined age, parity, progress of pregnancy, termination methods, obstetrics & neonatal complications, hematologic change, and treatment modality by medical records.RESULTS:
According to onset of disease, patients were divided into pre-pregnant diagnosed group(n=12) and during-pregnancy diagnosed group(n=25). Mean age of diagnosis was 29.4yr, 89.2% were nulliparous, and 51.4% were severe aplastic anemic patients. All patients underwent 50 pregnancy. Mean gestational period was 37wks, birth weight was 2569gram, and, except in 7 cases of abortion, 43 cases were delivered transvaginally or transabdominally(51.2% vs. 48.8%). Preeclampsia, eclampsia, preterm labor, restricted growth, and distress were complicated and decreased hemoglobin, hematocrit, reticulocyte, platelet were reversed after termination in pregnancy associated group. Treatment modality during pregnancy included transfusion, steroid, anti-lymphocytic globulin, anti-thymocytic globulin and IVGV, and remission rate was 45.5% in pregnancy associated group.CONCLUSION:
We concluded that pregnancy is associated with aplastic anemia as a high risk factor, and intensive treatment is needed.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Parity
/
Pre-Eclampsia
/
Reticulocytes
/
Birth Weight
/
Blood Platelets
/
Medical Records
/
Risk Factors
/
Diagnosis
/
Eclampsia
/
Hematocrit
Type of study:
Diagnostic study
/
Etiology study
/
Risk factors
Limits:
Female
/
Humans
/
Pregnancy
Language:
Korean
Journal:
Korean Journal of Obstetrics and Gynecology
Year:
1999
Type:
Article
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