Multi-modality MRI observation on whole brain structure abnormalities in patients with cervical spondylotic pain / 中国医学影像技术
Chinese Journal of Medical Imaging Technology
;
(12): 1286-1291, 2020.
Article
in Chinese
| WPRIM
| ID: wpr-860900
ABSTRACT
Objective:
To observe the microstructure abnormalities of gray matter and white matter in patients with cervical spondylotic pain (CSP) using voxel based morphometry (VBM) technology and diffusion tensor imaging (DTI).Methods:
Totally 31 CSP patients (CSP group) and 30 age and sex matched healthy volunteers (control group) underwent three dimensional T1 scanning of whole brain and DTI. Visual analogue scale (VAS) was performed on patients in CSP group, Hamilton Anxiety Scale (HAMA), Hamilton Depression Scale (HAMD) and Montreal Cognitive Assessment (MoCA) were performed on both groups. The microstructures of brain gray matter and white matter were observed and compared between groups, and correlation of parameters being statistically different between groups with clinical indicators were analyzed.Results:
The gray matter volumes of the right precuneus, right superior temporal gyrus and right middle cingulum decreased in CSP group compare with those in control group, which were negatively correlated with VAS scores (rs=-0.397, -0.402, -0.388, all P0.05).Conclusion:
VBM technique combined with DTI could be used to evaluate the microstructural changes gray matter and white matter of brain in CSP patients, including decreased gray matter volume of right precuneus, right superior temporal gyrus and right middle cingulum, accompanied by microstructural abnormalities of white matter in bilateral superior longitudinal fasciculus.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Medical Imaging Technology
Year:
2020
Type:
Article
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