Research progresses of smart responsive 19F magnetic resonance nanomolecular imaging probes in diagnosis of tumors / 中国医学影像技术

ABSTRACT

Using smart responsive nanomolecular probes can realize tumor targeted imaging with rapid response, sensitive diagnosis and precise treatment under the guidance of imaging on detection of probe distributions and localization of tumors. MRI, especially 19F-MRI, has high sensitivity and low background noise. In recent years, smart responsive 19F-MR nanomolecular imaging probes had been applied for detecting changes of pH, enzyme activity, reducing microenvironment, hypoxia, light and thermo-responsive aspects. The research progresses of smart responsive 19F magnetic resonance nanomolecular imaging probes in diagnosis of tumors were reviewed in this article.