Longitudinal layer-specific strain imaging in evaluation of early changes of left ventricular systolic function and synchrony in patients with systemic lupus erythematosus / 中国医学影像技术

ABSTRACT

Objective: To explore the early changes of left ventricular systolic function and synchrony in systemic lupus erythematosus (SLE) patients with longitudinal layer-specific strain imaging. Methods: Forty-two SLE patients (SLE group) and 30 healthy subjects (control group) were collected. Two-dimensional gray-scale moving images of three long axial sections of the left ventricular apex were stored, and the parameters of the longitudinal strain (LS) and peak strain dispersion (PSD) were obtained. The differences of these parameters were compared between groups. According to SLEDAI-2000 scoring system, the patients were divided into inactive phase (SLE-) subgroup and active phase (SLE+) subgroup, and the differences of related parameters were further analyzed. Results: Compared with control group, except apical segment, the LS of global and segmental three-layer myocardium decreased in SLE group (all P0.05). Conclusion: Longitudinal layer-specific strain imaging can be used to sensitively evaluate the subclinical left ventricular myocardial changes in SLE patients.