Active simulation and imaging of human brain blood oxygenation level dependent signal / 中国医学影像技术

ABSTRACT

Objective: To active simulation and imaging of human brain blood oxygenation level dependent (BOLD) signal, taken which as gold standard and standard signal to detect the quality and detection rate of brain MRI functional magnetic resonance imaging (fMRI) based on the changes of gray amplitude of BOLD signals during imaging. Methods: A new excitation circuit that could simulate the BOLD of the human brain was used to achieve the stable rectangular wave output of different current amplitude, different frequency and different space ratio, and the BOLD signal of the human brain in the time domain was simulated. Results: Stable rectangular wave input and consistent detection rate were obtained with 3 different MR devices with different field strength. Conclusion: The same device has similar detection rate for the design of the same stimulus model, which can be used as the reference standard of the known and determined signal to analyze the detection rate and consistency of BOLD signal.