Observation on vulnerable coronary plaques in HIV-infected patients based on coronary CTA / 中国医学影像技术
Chinese Journal of Medical Imaging Technology
;
(12): 391-395, 2020.
Article
in Chinese
| WPRIM
| ID: wpr-861082
ABSTRACT
Objective:
To explore whether vulnerable coronary plaques in HIV-infected patients are different with those in non-HIV-infected ones, and to analyze the relative risk factors.Methods:
A total of 167 HIV-infected patients (HIV-infected group) and 185 non-HIV-infected patients(non-HIV-infected group) who underwent coronary CTA (CCTA) were collected. Vulnerable plaques were defined as those with two or more high-risk morphological features. The type, location and incidence of vulnerable coronary plaques were analyzed and compared between 2 groups, and the risk factors of vulnerable coronary plaques in HIV-infected patients were analyzed.Results:
There was no significant difference of baseline clinical data between the two groups. The most common types of vulnerable coronary plaques in 2 groups were both low attenuation plaques+positive remodeling, most located in the proximal segment of left anterior descending artery (segment 6). The incidence of vulnerable coronary plaques ≥1 coronary segments in HIV-infected patients was higher than that in non-HIV-infected patients (34.73% vs 24.32%,P<0.05). Vulnerable coronary plaques in HIV-infected patients were independently correlated with the duration of antiretroviral therapy (ART) drug (OR=1.29, 95%CI [1.04,1.59], P=0.02).Conclusion:
The incidence of vulnerable coronary plaques in HIV-infected patients was higher than that in non-HIV-infected patients. ART drug may be an independent risk factor for coronary plaque vulnerability in HIV-infected patients.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Etiology study
/
Risk factors
Language:
Chinese
Journal:
Chinese Journal of Medical Imaging Technology
Year:
2020
Type:
Article
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