Echocardiographic observation on myocardial ischemia reperfusion injury after percutaneous coronary intervention / 中国医学影像技术

ABSTRACT

Objective: To evaluate changes of myocardial ischemia reperfusion injury (MIRI) after percutaneous coronary intervention (PCI) using regular echocardiography and 2D-STE. Methods: Thirty-two myocardial infarction patients who would underwent emergency PCI were included, among them 15 demonstrated clinical MIRI after PCI, while the other 17 not. Regular and two-dimensional speckle tracking echocardiography (2D-STE) were performed before (within 8 h) and after (within 2 h) PCI for evaluation on left ventricular structure, diastolic and systolic function and global longitudinal strain (GLS). All the echocardiographic parameters were compared between and within groups. Results: There was no significant difference of left heart diameter nor wall thickness between 2 groups before and after PCI (all P>0.05). Patients without MIRI showed no significant change of diastolic function, while those with MIRI showed reduced diastolic function demonstrated by decreased mitral flow velocity and annular velocity in early-diastole (E and e), and increased E/e (P<0.05). The eject fraction (EF) and GLS were significantly improved after PCI in patients without MIRI, whereas no change of EF but reduced GLS was observed in patients with MIRI. Conclusion: Patients with clinical MIRI after PCI suffered from reduced diastolic function and GLS. Regular echocardiography and 2D-STE should be combined to examine patients with MIRI after PCI.