Intraluminal CT values for evaluating stenosis of calcified coronary artery / 中国医学影像技术

ABSTRACT

Objective: To observe the accuracy of intraluminal CT values of coronary artery across calcification and the corrected coronary opacification(CCO)difference in evaluation on stenosis severity of coronary artery during computed tomography angiography (CCTA). Methods: Coronary artery calcifications (CAC) were detected in 233 main branches of coronary arteries(left anterior descending artery, left circumflex artery and right coronary artery) with CCTA. According to the degree of stenosis, the vessels were divided into mild stenosis group, moderate stenosis group, severe stenosis group and total occlusion group, respectively. The accuracy of CCO difference for evaluating coronary stenosis were analyzed and compared among groups. Results: CCO difference across calcification was significantly higher in total-occlusion group than in the other 3 groups (P0.05), while were higher in severe stenosis group and moderate stenosis group than in mild stenosis (P<0.001). Taken 0.086 9 as the cut-off point of CCO difference across calcified coronary artery, the sensitivity, specificity, positive predictive value and negative predictive value was 76.67%, 75.47%, 91.39% and 48.78% for diagnosing coronary artery stenosis ≥50%, respectively, while taken 0.207 0 as the cut-off point, the sensitivity, specificity, positive predictive value and negative predictive value was 91.84%, 79.89%, 54.88% and 97.35%, respectively for diagnosing total-occlusion of coronary artery. Conclusion: CCO difference across calcified coronary artery elevated as stenosis severity increased. Taking CCO difference across calcified coronary artery as an index might improve the accuracy of evaluating coronary artery calcification and stenosis.