Three-dimensional echocardiography combined with myocardial contrast echocardiography for assessment of myocardial dysfunction in patients with type 2 diabetes mellitus / 中国医学影像技术

ABSTRACT

Objective: To explore the value of real-time three-dimensional echocardiography (RT-3DE) combined with myocardial contrast echocardiography (MCE) in evaluating myocardial dysfunction in type 2 diabetes mellitus (T2DM) patients. Methods: Totally 58 T2DM patients were divided into group (T2DM isolated ) and group Ⅱ (T2DM associated with microvascular complications, each n=29). Group C included 32 normal individuals. The standard deviation (Tmsv16-SD, Tmsv12-SD, Tmsv6-SD) and the maximum time difference (Tmsv16-Dif, Tmsv12-Dif, Tmsv6-Dif) of the time to the minimum systolic volume of left ventricle were measured with RT-3DE. MCE was performed to obtain perfusion measurement of each segment of ventricular wall, including the acoustic intensity (A), microvascular flow velocity (β) and A•β. Results: There were statistically significant differences in all synchronize measurements except Tmsv6-Dif between group Ⅱ and group C (all P0.05). Conclusion: Left ventricular desynchrony can be observed in T2DM patients with or without microvascular complications. Myocardial perfusion reduce in T2DM patients presenting as diffuse damage, which aggravated with microvascular complications in other organs.