Comparative study of conventional MRI between Duchenne muscular dystrophy and Becker muscular dystrophy / 中国医学影像技术

ABSTRACT

Objective: To investigate the value of conventional MRI in differential diagnosis of Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD). Methods: The imaging data of the hip and thigh muscles of 697 patients with dystrophinopathy were retrospectively analyzed, and the similarities and differences of signs between DMD and BMD were compared. Results: The distribution of muscle fat infiltration in DMD and BMD patients was consistent, the total fat infiltration degree of DMD patients was higher than BMD patients (P=0.034), with the most obvious gluteus maximus, rectus femoris and sartorius; there was no significant difference in the degree of total muscle edema (P=0.065), however, the edema of the posterior thigh and sartorius of DMD was significantly higher than that of BMD. The selective involvement of muscle atrophy and hypertrophy was consistent between DMD and BMD patients, the frequency of atrophy of BMD lateral femoris, middle femoris, medial femoris, Semimembranosus and long head of biceps was significantly higher than that of DMD (P0.05). Conclusion: Conventional MRI can differentiate DMD from BMD.