18F-FDG PET/CT in diagnosis of renal cell carcinoma with venous tumor thrombosis / 中国医学影像技术

ABSTRACT

Objective: To explore the diagnosis value of 18F-FDG PET/CT for renal cell carcinoma (RCC) with venous tumor thrombosis (VTT). Methods: PET/CT data of 27 patients with pathologically confirmed RCC with VTT were analyzed retrospectively. PET/CT grading was compared with clinical grading for classification of VTT. According to pathological findings, the patients were divided into venous wall invasion group and venous wall noninvasion group. SUVmax of primary tumor, of VTT and inferior vena cava diameter were compared between two groups. Results: The average SUVmax of VTT was 6.98±5.50 in 27 cases with 100% (27/27) detection rate for VTT. Correct classification of VTT was performed in 26 cases with PET/CT, the accuracy rate was 96.30% (26/27). The average SUVmax of bland thrombosis (BT) was 1.30±0.28 in 8 cases, and the diagnostic accuracy was 87.50% (7/8). SUVmax of VTT was significantly higher than that of BT (P0.05). Conclusion: PET/CT has high detection accuracy for RCC with VTT and BT, also for tumor thrombus classification, but has limited ability to evaluate vein wall tumor invading.