Progresses of cardiac MRI in diagnosis of myodystrophic cardiomyopathy / 中国医学影像技术

ABSTRACT

Muscular dystrophy is a group of heterogeneous diseases with multiple subtypes, manifesting with progressive weakness and degeneration of skeletal muscle. Duchenne and Becker muscular dystrophy are the two most common types. The myocardium can be involved by muscular dystrophy, and heart-related diseases become the leading cause of death. Early detection of heart involvement with effective examination is of great value to improve the prognosis of patients. Cardiac MRI, including gadolinium delayed enhancement, T2 weighted black blood sequence, T2 mapping, native T1 mapping, extracellular volume and myocardial strain, can detect cardiac injury in the early stage of disease and provide strong evidences for early intervention and treatment, also measure left ventricular volume and left ventricular ejection fraction accurately and quantitatively, therefore having significant advantages in standardized treatment and evaluation of new therapies. The progresses of cardiac MRI in diagnosis of myodystrophic cardiomyopathy were reviewed in this paper.