CT-guided methylene blue and/or Hookwire localization of pulmonary ground-glass nodules before video-assisted thoracoscopic surgery / 中国医学影像技术

ABSTRACT

Objective:To explore the clinical application value of CT-guided methylene blue staining and/or Hookwire localization of pulmonary ground-glass nodule (GGN) before video-assisted thoracoscopic surgery (VATS). Methods: Totally 141 patients with 160 GGN underwent VATS after CT-guided methylene blue staining and/or Hookwire implantation for localization of nodules. The success rate of localization, puncture complications and success rate of surgery were calculated. Results: All GGN were successfully located and resected. Among 160 nodules, 18 were located with stained with methylene blue, 12 with Hookwire implantation, while 130 nodules were located with combination of two methods, and the success rates of methylene blue staining, Hookwire implantation and combination of these two methods were all 100%. Small amount of pulmonary hemorrhage and pneumothorax were observed in 25 and 38 cases respectively during puncture, including 13 cases with both pulmonary hemorrhage and pneumothorax. Postoperative pathology showed that 117 nodules were malignant and 43 were benign nodules. Conclusion: CT-guided methylene blue staining and/or Hookwire implantation before VATS can accurately locate GGN, reduce puncture complications and improve the success rate of resection.