Immunological Activities of Korean Mistletoe Extract ( Viscum album coloratum ; KM - 110 ) / 대한면역학회지
Korean Journal of Immunology
;
: 571-582, 1997.
Article
in Korean
| WPRIM
| ID: wpr-86128
ABSTRACT
Immunological effect of the extract (KM-110) from Korean mistletoe (Viscum album coloratum) was examined. Lymphocytes obtained from KM-110-administrated mice showed increased responsiveness to mitogens, concanavalin-A (Con.A) and lipopolysaccharide (LPS). In order to study cytokine induct ability of the KM-110, macrophages from the Balb/c mice were cultivated in the medium containing the extract. the macrophages were shown to induce secretion of tumor necrosis factor-alpha (TNF-alpha), interleukin 1 and 6 (IL-1, IL-6) and interferon-gamma (INF-gamma). We then tested antitumor activity of the macrophages activated by the KM-110. Peritoneal macrophages harvested from the KM110-treated Balb/c mice exhibited cytotoxicity against the syngeneic 3LL carcinoma cells. ...continue...
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Mistletoe
/
Lymphocytes
/
Interferon-gamma
/
Interleukin-1
/
Tumor Necrosis Factor-alpha
/
Macrophages, Peritoneal
/
Viscum
/
Viscum album
/
Macrophages
/
Mitogens
Limits:
Animals
Language:
Korean
Journal:
Korean Journal of Immunology
Year:
1997
Type:
Article
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