CEUS in evaluating invasiveness of papillary thyroid carcinoma and relationship with pathological microvessel density / 中国医学影像技术

ABSTRACT

Objective: To explore the value of CEUS in evaluating invasiveness of papillary thyroid carcinoma (PTC) and the relationship with pathological microvessel density (MVD). Methods: CEUS characteristics of 52 patients with PTC confirmed by surgical pathology were analyzed. MVD was counted in the postoperative pathological sections, and the relationship between MVD and CEUS features was analyzed. Results: The peripheral MVD of PTC was higher than that in the central PTC (t=0.024, P=0.041), and peripheral MVD in patients with cervical lymph node metastasis were higher than that of non-metastatic patients (P=0.039). The time-intensity curve AUC of the peripheral area of the nodules was positively correlated with MVD count of the peripheral areas of the nodules and the total nodules (r=0.45, 0.41, both P<0.05). Conclusion: CEUS characteristics of papillary thyroid carcinoma are correlated with MVD. CEUS quantitative analysis technique has certain value of evaluating the invasiveness PTC.