Molecular imaging for magnetotactic bacterial magnetosomes and related MRI reporter genes / 中国医学影像技术

ABSTRACT

Magnetotactic bacteria encode iron nanoparticles-magnetosomes, which are regulated by a group of genes, have organelle-like structures. Their unique structures have received much attention in recent years due to the distinctive properties, including applications of purified magnetosomes in magnetic particles imaging and of magnetosome-associated regulatory genes in molecular imaging as MRI reporter genes. Although the research on magnetosomes has been increasing in recent years, its application as MRI reporter gene is still in its infancy. Molecular imaging studies of magnetosomes and related genes as MRI reporter genes were reviewed in this article.