MRI measurement of parietal lobe volume in different genders of Han Chinese / 中国医学影像技术

ABSTRACT

Objective: To measure the volume of parietal lobe of different genders of Han nationality in China. Methods A multi-center study was conducted with 100 healthy volunteers aged 18 to 70 years old. 3D T1W magnetization prepared rapid acquisition gradient echo sequence was used to perform whole-brain scan, and the volume of left and right parietal lobe and total brain volume were measured manually. After standardization, the differences of parietal volume were compared between male and female and between left and right sides, and the correlation between parietal volume and age was evaluated. Results In male, the left measured parietal volume was (113.05±11.14)cm3, the right was (111.75±10.61)cm3, and the total brain volume was (1 605.90±115.05)cm3. In female, the left measured parietal volume of female was (103.75±9.96)cm3, the right was (102.22±9.31)cm3, and the total brain volume was (1 444.56±93.26)cm3. There was no statistically significant difference of parietal volume between left and right sides in male (P>0.05), while there was a statistically significant difference in female (P0.05). Conclusion Both total brain volume and parietal volume of Han Chinese male are significantly larger than those of female. There is no difference between the left and right parietal lobes in male, while the left side is slightly larger than right side in female. A reduction in parietal volume with age is found in male.