Transrectal ultrasound combined with seminal plasma elastase in diagnosis of male infertility caused by chronic seminal vesiculitis / 中国医学影像技术

ABSTRACT

Objective: To investigate the value of transrectal ultrasound combined with seminal plasma elastase (SPE) in diagnosis of male infertility caused by chronic seminal vesiculitis (CSV). Methods Transrectal ultrasonography was performed in 106 patients with male infertility caused by CSV (infertility group) and 106 healthy men (control group), and SPE was detected in two groups. The differences of seminal vesicle ultrasound parameters and SPE were compared between two groups. The correlations between SPE and seminal vesicle parameters were analyzed. ROC curves were used to evaluate the diagnostic efficiency of SPE combined with seminal vesicle ultrasound parameters on male infertility caused by CSV. Results: The short diameter of seminal vesicle, inner diameter of gland tube, the peak systolic velocity (PSV), resistance index (RI) and SPE level in infertility group were higher than those in control group (all P<0.01). The short diameter of seminal vesicle, inner diameter of gland tube, PSV, RI and SPE were impact factors of male infertility caused by CSV (all P<0.05). SPE was positively correlated with PSV, RI and short diameter of seminal vesicle (r=0.732, P<0.001; r=0.647, P=0.004; r=0.526, P=0.007). SPE combined with PSV, RI and short diameter of seminal vesicle could be used to diagnose male infertility caused by CVS (all P<0.05), among which SPE combined with PSV had the most effective diagnostic value, the area under ROC was 0.73, the sensitivity and specificity was 0.73 and 0.70, respectively. Conclusion: Transrectal ultrasound combined with SPE have certain clinical diagnostic value for male infertility induced by CSV.