CEUS and planewave ultrasensitive imaging analysis of thyroid papillary carcinoma / 中国医学影像技术

ABSTRACT

Objective To observe manifestations of thyroid papillary carcinoma (PTC) in CEUS and planewave ultrasensitive imaging (AngioPLUS). Methods CEUS and AngioPLUS features of histopathologically proved PTC in 83 patients were retrospectively analyzed. According to CEUS enhancement, the patients were divided into hypo-enhancement group, iso-enhancement group and hyper-enhancement group. The differences of the peak intensity (PI) between lesion and adjacent thyroid tissue (ΔPI) were compared among 3 groups. The correlation of PI, ΔPI and CEUS enhancement of the lesions were evaluated, so as the correlation of CEUS enhancement, PI, ΔPI and the microvascular distribution showed with AngioPLUS. Results The differences of ΔPI among the 3 groups were statistically significant (χ2=52.35, P<0.001). ΔPI of hypo-enhancement group was less than that of iso-enhancement group (Z=-6.45, P<0.001) and hyper-enhancement group (Z=-3.99, P<0.001). ΔPI of iso-enhancement group was less than that of hyper-enhancement group (Z=-3.73, P<0.001). The differences of PI were statistically significant among 3 groups (F=34.97, P<0.001). PI of hypo-enhancement group was less than that of iso-enhancement group and hyper-enhancement group (both P<0.001). No significant difference was found for PI between iso-enhancement group and hyper-enhancement group (P=0.322). PI (rs=0.650, P<0.001) and ΔPI (rs=0.798, P<0.001) both had positive correlation with CEUS enhancement of the lesions. CEUS enhancement (rs=0.768, P<0.001), PI (rs=0.442, P<0.001) and ΔPI (rs=0.647, P<0.001) all had positive correlation with microvascular distribution demonstrated with AngioPLUS of the lesions. Conclusion CEUS enhancement of PTC showes positive correlation with microvascular distribution demonstrated with AngioPLUS of the lesions, which may be used to evaluate the perfusion indirectly of the lesions.