Ultrasonographic characteristics of extramammary Paget's disease / 中国医学影像技术

ABSTRACT

Objective To explore the ultrasonographic features of extramammary Paget's disease (EMPD). Methods The ultrasonographic data of 41 patients with EMPD confirmed by pathology were retrospectively analyzed, and the ultrasonographic features of EMPD were observed. Results Among the 41 patients of EMPD, lesions located at vulva in 33 cases, at groin in 2, at perianal in 2 cases, while at upper chest wall, lower abdominal wall, forehead and thumb in 1 case, respectively. Among 36 patients with ultrasonographic found lesions, EMPD could be divided into diffuse type and mass type according to the morphology of the lesions. There were 31 diffuse type lesions with irregular shape and unclear margin. Ultrasound showed skin thickening in 30 lesions and no thickening in 1, hypoechoic echo in 8 and slightly hypoechoic echo in 23, while CDFI blood flow demonstrated grade 0 in 2, grade 1 in 6, grade 2 in 11, grade 3 in 12. Inguinal abnormal lymph nodes were found in 9 patients with diffuse type EMPD. There were 5 patients of mass type EMPD with clear margins, among them ultrasound showed 1 patient with skin thickening and 4 without thickening, and hypoechoic lesions were found in 3 patients and slightly hypoechoic lesions in 2 patients. The shape of 4 lesions were regular and 1 was irregular, 1 lesion with CDFI blood flow of grade 0, 2 of grade 1, 1 of grade 2, 1 of grade 3. The abnormal inguinal lymph nodes were found in 3 patients. Ultrasonography showed no obvious abnormality in the other 5 patients (5/41, 12.20%). Conclusion Ultrasound could sensitively identify abnormal echo and blood flow in EMPD lesions. Clinical manifestations should be considered in ultrasound diagnosis of EMPD.