Progress in targeted therapy for brain metastasis from non-small-cell lung cancer positive for ALK gene fusion / 中国肿瘤临床
Chinese Journal of Clinical Oncology
;
(24): 95-98, 2020.
Article
in Chinese
| WPRIM
| ID: wpr-861532
ABSTRACT
The incidence of anaplastic lymphoma kinase (ALK) gene fusion in non-small-cell lung cancer (NSCLC) is approximately 2%-7%. In cases of lung cancer with this gene mutation, the probability of brain metastasis, which seriously affects quality of life and shortens survival time, is higher. In recent years, survival time has significantly increased among ALK gene fusion-positive NSCLC patients with brain metastasis owing to continuous advances in the development of ALK-tyrosine kinase inhibitors (TKIs). This paper reviews the progress in the research on ALK-TKI use in the treatment of brain metastasis from NSCLC.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Clinical Oncology
Year:
2020
Type:
Article
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