Immune checkpoint inhibitors for non-small cell lung cancer: Research progress of real-world studies / 中国肿瘤临床
Chinese Journal of Clinical Oncology
;
(24): 640-646, 2020.
Article
in Chinese
| WPRIM
| ID: wpr-861631
ABSTRACT
Several immune checkpoint inhibitors (ICIs) have been approved for use in patients with advanced non-small cell lung cancer (NSCLC) based on the results of randomized controlled trials (RCTs), bringing new hope to patients with such disease. However, the applicability of the RCT results is limited due to their strict inclusion criteria and specific clinical settings. Real-world studies (RWS) can integrate data from real-life practice with long-term clinical observations and follow-up, therefore building up the real-world evidence to complement that provided by conventional clinical trials. ICIs have been used in clinical practice in multiple countries and areas for several years. Here, we aim to provide an overview of the efficacy and safety of ICIs in patients with NSCLC included in the large expanded access program and multicenter retrospective observational studies and review the impact of different populations to provide a reference for ICIs use in China.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Controlled clinical trial
/
Observational study
Language:
Chinese
Journal:
Chinese Journal of Clinical Oncology
Year:
2020
Type:
Article
Similar
MEDLINE
...
LILACS
LIS