Advances in Research on IL-37 in Inflammatory Bowel Disease / 胃肠病学
Chinese Journal of Gastroenterology
; (12): 309-313, 2020.
Article
in Zh
| WPRIM
| ID: wpr-861682
Responsible library:
WPRO
ABSTRACT
Inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn's disease (CD), is a chronic and nonspecific intestinal inflammatory disease. Immune response disorder is one of the important links in the pathogenesis of IBD. Cytokines participate in the development and remission of IBD by modulating immune response. Interleukin-37 (IL-37), an anti-inflammatory cytokine, can inhibit the excessive immune response through extracellular and intracellular pathways. Several studies have shown that IL-37 can limit intestinal inflammation damage and promote inflammation remission, and play an important protective role in IBD. This article reviewed the research progress on IL-37 in IBD.
Full text:
1
Index:
WPRIM
Language:
Zh
Journal:
Chinese Journal of Gastroenterology
Year:
2020
Type:
Article