Research Progress on Quantitative Detection of Hepatic Steatosis in Nonalcoholic Fatty Liver Disease / 胃肠病学

ABSTRACT

Nonalcoholic fatty liver disease (NAFLD) is a multi-system disease that also affects extrahepatic organs and overall metabolic regulation pathways, increasing the risk of type 2 diabetes, cardiovascular disease, and chronic kidney disease. The progressive form of NAFLD is called nonalcoholic steatohepatitis (NASH), which can be further developed into liver cirrhosis and liver cancer. Early screening, grading the disease and assessment of drug treatment response are the focus of current research. The detection of liver fat content is the key to early diagnosis of NAFLD, and it is also a reliable indicator for evaluating the drug efficacy in clinical trials. This article reviewed the noninvasive diagnostic techniques for the quantitative detection of liver fat content.