Advances in Research on Correlation of Microsatellite Instability With Colorectal Cancer / 胃肠病学

ABSTRACT

Colorectal cancer (CRC) has a high morbidity and mortality rate worldwide. Current studies indicate that CRC is a heterogeneous disease caused by long-term accumulation and joint action of genetic instability caused by various reasons. Microsatellite instability (MSI) is one of the main pathways. This article reviewed the advances in research on correlation of MSI with CRC.