Clinical Applications of Circulating Tumor DNA in Diagnosis of Gastric Cancer / 胃肠病学

ABSTRACT

Gastric cancer is the fifth most common type of cancer in the world and the third leading cause of cancer death. Conventional treatment for gastric cancer includes surgical resection and adjuvant therapy. More than 50% of patients are reaching the advanced stage when diagnosed, because they do not have typical symptoms at early stage. Researchers continue to investigate more sensitive methods for detecting the occurrence and development of gastric cancer. In addition to new serum tumor biomarkers through proteomics, new concept such as circulating tumor DNA (ctDNA) has also been introduced. This article reviewed the clinical application of ctDNA in diagnosis of gastric cancer.