Advances in Research on Relationship Between Fusobacterium nucleatum and Cancer / 胃肠病学
Chinese Journal of Gastroenterology
;
(12): 119-122, 2019.
Article
in Chinese
| WPRIM
| ID: wpr-861879
ABSTRACT
The disturbance of intestinal flora is closely related to the development of tumors. Studies showed that oral symbiotic strain Fusobacterium nucleatum was significantly enriched in a variety of tumors and promoted the disease progression, indicating poor prognosis of patients. Molecular mechanism studies found that Fusobacterium nucleatum could activate host cell cancer-related signaling pathways, trigger chronic inflammation, and suppress immune surveillance to enhance cancer cell proliferation, invasion, metastasis and anti-apoptosis. This article reviewed advances in research on relationship between Fusobacterium nucleatum and cancer.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Gastroenterology
Year:
2019
Type:
Article
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