Genetic Study of Inflammatory Bowel Disease and its Clinical Application / 胃肠病学
Chinese Journal of Gastroenterology
;
(12): 1-4, 2019.
Article
in Chinese
| WPRIM
| ID: wpr-861881
ABSTRACT
Inflammatory bowel disease (IBD) is an idiopathic and chronic non-specific inflammatory disease of gastrointestinal tract. Abnormal immune response in intestinal mucosa toward commensal microbiota together with intestinal mucosal barrier defects, genetic and environmental factors might be associated with the pathogenesis of human IBD. In recent years, great progress has been made in genetic study of IBD, providing important help for clinical translation and application. Genetic analysis will help us to explain the etiology and lesional areas of IBD, predict the disease behaviors and effectiveness of treatment, thereby benefits the clinical diagnosis and treatment of the disease. This review summarizes the latest achievements and new progresses in genetic study and clarifies the potential value of genetic study in management of IBD.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Prognostic study
Language:
Chinese
Journal:
Chinese Journal of Gastroenterology
Year:
2019
Type:
Article
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