Percutaneous mechanical aspiration thrombectomy with AngioJet for treatment of acute lower extremity deep vein thrombosis after surgical operation / 中国介入影像与治疗学

ABSTRACT

Objective; To evaluate the effect of percutaneous mechanical aspiration thrombectomy (PMT) with AngioJet for treatment of acute deep venous thrombosis (DVT) after surgical operation. Methods: Data of 103 patients with acute lower extremity DVT after surgical operation who underwent AngioJet PMT were retrospectively analyzed. The affected-healthy side diameter differences of thigh and leg, as well as peripheral blood D-dimer levels were compared before and 7 days after AngioJet PMT. The clearance rate of thrombosis for each segment of lower limb veins was detected, the intraoperative and postoperative adverse reactions were counted. Results: Seven days after AngioJet PMT, both the affected-healthy side diameter difference of thigh and leg decreased, so did the peripheral blood D-dimer value (all P<0.05). Effective thrombosis clearance rate (grade Ⅱ, III) of iliac vein, femoral vein and popliteal vein was 97.37% (74/76), 98.06% (101/103) and 94.83% (55/58), respectively, while grade III clearance rate of the above segments was 77.63% (59/76), 70.87% (73/103) and 55.17% (32/58), respectively, of iliac vein and femoral vein were all higher than that of popliteal vein (both P<0.01). Transient arrhythmia occurred in 11 cases (11/103, 10. 68%) during thrombectomy, and returned to normal within 2 min after stopping thrombectomy. Hemorrhage at the puncture site occurred in 3 cases, while 38 cases were found with transient hemoglobinuria, 2 cases with transient creatinine elevation and 3 cases with limb pain. No new pulmonary embolism nor acute renal failure occurred. The filters were failed to be removed in 2 cases, while removed filters were found with obvious thrombi in 6 cases. Conclusion: Percutaneous mechanical aspiration thrombectomy with AngioJet was effective and safe for treatment of acute lower extremity DVT.