Safety and efficacy of coaxial puncture 125I particle implantation in treatment of pancreatic head and neck cancer / 中国介入影像与治疗学
Chinese Journal of Interventional Imaging and Therapy
;
(12): 548-551, 2020.
Article
in Chinese
| WPRIM
| ID: wpr-861928
ABSTRACT
Objective:
To observe the safety and efficacy of coaxial puncture 125I seed implantation in treatment of locally advanced pancreatic head and neck cancer.Methods:
Totally 21 patients with locally advanced pancreatic cancer were retrospectively analyzed. Preoperative planning was performed with treatment planning system (TPS) and fan-shaped distributed system simulated in the same plane. 125I seeds were implanted using coaxial puncture technology, and was operative plan real-timely adjusted during operation. After operation, CT images were imported into TPS for dose verification. Abdominal CT scanning were performed 2, 4 and 6 months after operation to evaluate the treatment efficiency and local control rate, and intraoperative and postoperative complications were counted.Results:
The operations were successfully completed in all patients. The effective rate of treatment 2, 4 and 6 months after operation was 38.10% (8/21), 47.62% (10/21) and 52.38% (11/21),and the local control rate was 95.24% (20/21), 80.95% (17/21) and 80.95% (17/21), respectively. Intraoperative complications included 2 cases of local abdominal hemorrhage, 2 cases of subcutaneous soft tissue hematoma and wrong puncture of pancreatic duct in 1 case. Post operation, fever and appetite loss occurred in 10 and 3 cases, respectively. Among 21 patients, grade 0 and grade acute radiation enteritis were observed in 18 and 3 cases, respectively.Conclusion:
Coaxial puncture 125I particle implantation technology is safe and effective for treatment of locally advanced pancreatic head and neck cancer.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Interventional Imaging and Therapy
Year:
2020
Type:
Article
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