Research progress of drug-coated balloon therapy for lower extremity atherosclerotic disease / 中国介入影像与治疗学

ABSTRACT

Lower extremity artery disease (LEAD) is a kind of disease caused by atherosclerosis, which leads to narrowing and occlusion of lower extremity artery and causes ischemia symptoms of corresponding limbs. Endovascular intervention has become the main treatment method for LEAD, mainly including percutaneous transluminal angioplasty (PTA) and stent implantation, but high restenosis rate is still unavoidable after treatment. Drug-coated balloon (DCB) can inhibit intimal hyperplasia and inflammation while avoid the retention of foreign bodies, having good therapeutic effects on both primary lesions and in-stent restenosis. The principle of DCB therapy, application status and research advancements of DCB for LEAD were reviewed in this article.