CT-guided microwave ablation and biopsy of highly suspected malignant ground-glass nodule of lung with co-axle technique / 中国介入影像与治疗学

ABSTRACT

Objective: To observe the feasibility of CT-guided microwave ablation and biopsy of highly suspected malignant pulmonary ground-glass nodule (GGN) with co-axle technique. Methods: Totally 54 patients with highly suspected malignant pulmonary single GNN (with diameter of 10-25 mm) were retrospectively analyzed, including 26 underwent CT-guidance microwave ablation and biopsy with co-axle technique (ablation synchronous biopsy group) and 28 underwent simple puncture biopsy (biopsy group). The rates of pathological diagnosis, hemorrhage and pneumothorax were compared between 2 groups. Results: All patients underwent successful operation, the success rate was both 100% in 2 groups. The rate of pathological diagnosis was 88.46% (23/26), of pneumothorax was 26.92% (7/26) in ablation synchronous biopsy group, while in biopsy group was 92.86% (26/28) and 32.14%(9/28), respectively (both P>0.05). The rate of hemorrhage in ablation synchronous biopsy group was 30.77%(8/26),lower than that of biopsy group (42.86% [12/28], χ2=5.962,P=0.028). Conclusion: CT-guided microwave ablation and biopsy of highly suspected malignant pulmonary GGN with co-axle technique is safe and effective with lower bleeding risk compared with biopsy alone.