Diagnostic value of high-frequency ultrasonography for Paget disease of breast / 中国介入影像与治疗学

ABSTRACT

Objective: To investigate the diagnostic value of high-frequency ultrasound for Paget disease of breast (PDB). Methods:High-frequency ultrasound data of 30 patients with pathology approved PDB were retrospectively analyzed, including 13 cases complicated with invasive ductal carcinoma (IDC). Ultrasonic appearances of PDB with or without IDC were compared. Results: Ultrasonic features of PDB included hypo-echogenicity in nipple, thicken areola skin, mammary nodules, calcification, dilated duct and enlarged axillary lymph nodes. Compared with PDB without IDC, PDB complicated with IDC showed more mammary nodules (P=0.001) and enlarged axillary lymph nodes (P=0.002). No significant difference of breast imaging reporting and data system (BI-RADS) classification, hypo-echogenicity in nipple, thicken areola skin, calcification nor dilated duct rate was found between groups (all P>0.05). Conclusion: PDB have certain ultrasonic characteristics. High-frequency ultrasound is helpful to diagnosis and assessment of PDB.