Differential diagnosis of cerebellum cystic-solid hemangioblastoma and pilocytic astrocytoma according to MRI enhancement degree / 中国介入影像与治疗学

ABSTRACT

Objective: To investigate the value of MRI enhancement degree in differential diagnosis of cerebellum cystic-solid hemangioblastoma and pilocytic astrocytoma. Methods: MRI data of 30 patients with cerebellum cystic-solid hemangioblastoma and 30 patients with cerebellum cystic-solid pilocytic astrocytoma confirmed by operation and pathology were retrospectively analyzed. The enhancement value of the solid component of the lesion was calculated, then ROC curve was drawn, and the diagnostic effect of the solid component enhancement level was evaluated. Results: Among 30 cases of cerebellum cystic-solid hemangioblastoma, cystic nodules were in 15 cases, while solid masses with cystic changes were observed in other 15 cases, and the parenchyma part was uniformly strengthened. Among 30 cases of cerebellum cystic-solid pilocytic astrocytoma, cystic nodules were detected in 11 cases, where as solid masses with cystic changes were noticed in 19 cases, 21 cases had uniform enhancement of parenchyma and 9 cases showeduneven enhancement. The parenchyma enhancement degree of cerebellum cystic-solid hemangioblastoma was 4.20 (3.28,4.84), of cerebellum cystic-solid pilocytic astrocytoma was 1.95 (1.49,2.43) (F=72.69,P<0.01). The specificity and sensitivity of diagnosis of cerebellum cystic-solid hemangioblastoma was 88.9% and 92.9%, respectively. Taken the enhancement amplitude 2.58 as the threshold, the AUC was 0.95. Conclusion: The degree of MRI enhancement of solid tumor components is helpful to distinguishing cerebellum cystic-solid hemangioblastoma and pilocytic astrocytoma.