Impact factors of occluder choice for transcatheter closure of adult large atrialseptal defect / 中国介入影像与治疗学

ABSTRACT

Objective: To analyze the impact factors of occluder choice for transcatheter closure of adult large atrial septal defect (ASD). Methods: Data of 65 patients with large ASD were retrospectively analyzed. The relationships of occluder choice for transcatheter closure of ASD and the diameter, shape and edge of defect were observed. Results: ASD in all patients were successfully occluded, with 40 mm diameter occluders in 26 cases, 42 mm diameter occluders in 24 cases and ≥ 44 mm diameter occluders in 15 cases. There was no difference of defect maximum diameter (Dmax), minimum diameter (Dmin), Dmin/Dmax nor the added value of occluder (all P>0.05) among the above three, whereas there were statistical differences of Dmax, Dmin and the added value of Dmin/Dmax<0.80 (n=24) and ≥0.80 (n=41) occluders (all P<0.05). Meanwhile, significant differences of diameter and the added value of occluders were noticed between patients with distance of defect aortic margin or posterior inferior margin <5 mm (n=45) and those ≥5 mm (n=20, all P<0.05). Conclusion: For intervention treatment of adult large ASD, the diameter, shape and edge of defect are the impact factors of choice of occluder.