Prognostic analysis for diabetic pyogenic liver abscess patients in different levels of haemoglobin treated with percutaneous catheter drainage / 中国介入影像与治疗学

ABSTRACT

Objective: To compare the prognosis of diabetic pyogenic liver abscess (PLA) patients with different levels of haemoglobin (HbA1c) treated with percutaneous catheter drainage (PCD), and to identify the predictors for overall recovery time (ORT) after PCD. Methods: Thirty-three diabetic PLA patients underwent PCD were retrospectively reviewed and divided into three groups based on HbA1c level, including group A (HbA1c<7%, n=11), group B (7%≤HbA1c<9%, n=9) and group C (HbA1c≥9%, n=13). The clinical success rate of PCD, ORT and recurrence rate of PLA were compared. Predictors of ORT were analyzed via univariate analysis (Log-rank test) and Cox multi-factor regression analysis. Results: The clinical success rate of PCD for treating PLA was 100% (33/33), with the mean ORT of (24.30±11.60) days. The mean catheter removal time and follow-up time was (27.76±12.03) days and (11.02±6.51) months, respectively. There was no significant difference of recurrence rate of PLA among three groups (P=0.140). However, significant difference of ORT (P=0.002) was found among three groups. Univariate analysis and multivariate analysis indicated that septic shock (hazard ratio [HR]=0.320, 95%CI [0.131, 0.777], P=0.012) and HbA1c≥7% (HR=0.249, 95%CI [0.104, 0.594], P=0.002) were predictors for ORT. Conclusion: For diabetic PLA patients, the higher level of HbA1c, the longer the ORT. Septic shock and HbA1c are predictors for ORT.