Clinical application of MRI-guided argon-helium cryoablation of tumors / 中国介入影像与治疗学

ABSTRACT

Objective To investigate the clinical value of MRI-guided argon-helium cyoablation in the treatment of tumors. Methods: MRI-guided argon helium cyoablation was performed in 90 tumor patients, including 52 cases of liver tumor, 10 of kidney tumor, 6 of chest wall tumor, 12 of pelvic tumor, 9 of limb tumors and 1 case of sciatic tumor. SE T1W, FSE T2W and SPGR T1W sequences were used to monitor the process of puncture and cyoablation. MRI findings and the complications during cyoablation were observed. Enhanced MRI was performed after cyoablation to evaluate the therapeutic efficacy. Results: All lesions could be clearly displayed with MRI during cyoablation, and the whole probes could be clearly showed on SPGR T1WI. A total of 24 patients with large lesions (maximum diameter 10.80-15.06 cm) underwent tumor cytoreduction therapy, the average times of cytoreduction therapy was 2.96±0.76. Among them, the part of lesion covered by ice-ball during cyoablaion showed no enhancement in 17 patients, while in the rest 7 patients, enhancement could be observed at the edge of lesions which became larger on enhanced MRI 1 month after the last treatment. In 66 patients underwent single time cyoablation, the lesions were all covered by the ice-ball during cyoablation treatment, and enhanced MRI showed complete ablation of lesions in 47 cases and partial ablation in 19 cases 1 month after cyoablation. Local bleeding around puncture point was observed in 11 patients, no serious complication occurred. Conclusion: MRI-guided argon-helium cyoablation can be used as an effective method in the treatment of tumor on different sites.