Early efficacy and impact factors of biliary stent in treatment of malignant obstructive jaundice / 中国介入影像与治疗学

ABSTRACT

Objective: To investigate the early efficacy and impact factors of biliary stent in treatment of malignant obstructive jaundice (MOJ). Methods: Clinical data of 232 patients with MOJ who underwent percutaneous transhepatic cholangial drainage (PTCD) and biliary stent implantation were analyzed retrospectively. The early postoperative outcomes were evaluated, and the impact factors of early postoperative outcomes were analyzed using univariate analysis and Logistic regression. Results: All 232 patients were successfully treated with PTCD and biliary stent implantation, and the drainage was performed. Among 232 patients, the treatment were markedly effective in 149 cases, effective in 36 cases, whereas ineffective in 47 cases at early postoperative stage, and the total effective rate was 79.74% (185/232). Univariate analysis showed that tumor type, obstruction level, length of obstruction, Child-Pugh grading, ascites, intrahepatic lesions, distant metastasis, tumor size, blood platelet (PLT), CA125 and postoperative biliary tract infection were important factors influencing early efficacy (all P<0.05). Logistic regression showed that Child-Pugh grading, PLT, CA125 and postoperative biliary tract infection were independent risk factors for early efficacy (all P<0.05). Conclusion: Biliary stent implantation has certain value in improving liver function and treating jaundice in patients with MOJ. Child-Pugh grading, PLT, CA125 and postoperative biliary tract infection are independent risk factors for early postoperative outcomes.