Pathogenesis of coronavirus disease 2019 with liver injury / 临床肝胆病杂志

ABSTRACT

Coronavirus disease 2019 (COVID-19) has become a major threat to global public health. In addition to injury in the respiratory system, some patients may have varying degrees of liver injury. With reference to related articles, this article analyzes the etiological characteristics and pathogenesis of COVID-19 and discusses the possible causes of COVID-19 with liver injury, including the direct effect of virus, inflammatory cytokine storm, drug-induced liver injury, hypoxic liver injury, and immune dysfunction. It is suggested that reasonable drugs should be selected in clinical practice to protect the liver and reduce the incidence rate of liver injury.